发明授权
- 专利标题： Sustained release formulations of water soluble peptides
- 专利标题（中）： 水溶性肽的缓释制剂
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申请号： US470072申请日： 1995-06-06
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公开(公告)号： US5639480A公开(公告)日： 1997-06-17
- 发明人: David Bodmer , Jones W. Fong , Thomas Kissel , Hawkins V. Maulding , Oskar Nagele , Jane E. Pearson
- 申请人： David Bodmer , Jones W. Fong , Thomas Kissel , Hawkins V. Maulding , Oskar Nagele , Jane E. Pearson
- 申请人地址： CHX Basel
- 专利权人： Sandoz Ltd.
- 当前专利权人： Sandoz Ltd.
- 当前专利权人地址： CHX Basel
- 优先权： HUX3974/90 19900625
- 主分类号： A61K9/16
- IPC分类号： A61K9/16 ; A61K9/50 ; A61K38/31 ; A61K9/14
摘要：
The invention discloses microparticles comprising a polypeptide, preferably somatostatin or an analog or derivative thereof, more preferably octreotide, in a polymeric matrix, preferably poly(lactide-co-glycolide)glucose. The invention also discloses sustained release formulations containing said microparticles and the use of said formulations in treating acromegaly and breast cancer.
公开/授权文献
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