发明授权
US5648212A Detection of inherited and somatic mutations of APC gene in colorectal
cancer of humans
失效
检测人类结肠直肠癌APC基因的遗传和体细胞突变
- 专利标题： Detection of inherited and somatic mutations of APC gene in colorectal cancer of humans
- 专利标题（中）： 检测人类结肠直肠癌APC基因的遗传和体细胞突变
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申请号： US289548申请日： 1994-08-12
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公开(公告)号： US5648212A公开(公告)日： 1997-07-15
- 发明人: Hans Albertsen , Rakesh Anand , Mary Carlson , Joanna Groden , Philip John Hedge , Geoff Joslyn , Kenneth Kinzler , Alexander Markham , Yusuke Nakamura , Andrew Thliveris , Bert Vogelstein , Raymond L. White
- 申请人： Hans Albertsen , Rakesh Anand , Mary Carlson , Joanna Groden , Philip John Hedge , Geoff Joslyn , Kenneth Kinzler , Alexander Markham , Yusuke Nakamura , Andrew Thliveris , Bert Vogelstein , Raymond L. White
- 申请人地址： MD Baltimore UT Salt Lake City JPX Tokyo GB2 Cheshire
- 专利权人： The John Hopkins University,University of Utah,Japanese Foundation for Cancer Research Cancer Institute,Zeneca Limited
- 当前专利权人： The John Hopkins University,University of Utah,Japanese Foundation for Cancer Research Cancer Institute,Zeneca Limited
- 当前专利权人地址： MD Baltimore UT Salt Lake City JPX Tokyo GB2 Cheshire
- 优先权： GBX9100962 19910116; GBX9100963 19910116; GBX9100974 19910116; GBX9100975 19910116
- 主分类号： C07K14/47
- IPC分类号： C07K14/47 ; C07K14/82 ; C07K16/32 ; C12N5/12 ; C12N15/12 ; C12Q1/68 ; C07H21/04 ; C07H21/02 ; C12P19/34
摘要：
Methods are provided for assessing mutations of the APC gene in human tissues and body samples. APC mutations are found in familial adenomatous polyposis patients as well as in sporadic colorectal cancer patients. APC is expressed in most normal tissues. APC is a tumor suppressor.
公开/授权文献
- US5966062A Magnetopermanent plate 公开/授权日：1999-10-12
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