Apparatus that provides an integrated approach for all management activities for hazardous substances used or generated at a facility, including form generation and compliance with the reporting requirements. The apparatus includes six functional groupings and a database schema or coordinator that integrates these groupings and allows them to share and exchange relevant information. The functional groupings include a hazardous materials index grouping (chemical profiles, waste profiles, Material Safety Data Sheets, etc.), a hazardous materials management grouping (MSDS generation, process definition, materials transfers, etc.), a human resource management grouping (training, exposure limits, etc.) and a hazardous commitment management grouping (compliance requirements and deadlines). Optionally, a hazardous waste management grouping (waste accumulations, Hazardous Waste Manifests, etc.) or a hazardous permit management grouping (permit approvals and renewals, etc.), or both, may be combined with all of the other four functional groupings to form an operating system. Optionally, the hazardous materials index grouping plus the hazardous materials management grouping plus the database schema may be combined with one of the other four functional groupings to form an operating system. Optionally, the hazardous materials index grouping plus the database schema may be combined with one of the other five functional groupings to form an operating system.