发明授权
- 专利标题: Use of aldosterone antagonists to inhibit myocardial fibrosis
- 专利标题(中): 使用醛固酮拮抗剂抑制心肌纤维化
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申请号: US579237申请日: 1996-03-28
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公开(公告)号: US5668124A公开(公告)日: 1997-09-16
- 发明人: Karl T. Weber
- 申请人: Karl T. Weber
- 专利权人: Weber; Karl T.
- 当前专利权人: Weber; Karl T.
- 主分类号: A61K45/00
- IPC分类号: A61K45/00 ; A61K31/00 ; A61K31/56 ; A61K31/585 ; A61P9/00 ; C07J1/00 ; C07J21/00 ; A61K31/71
摘要:
This invention discloses a method of using an aldosterone antagonist such as spironolactone, at a dosage which does not disrupt a patient's normal electrolyte and water-retention balance, to inhibit myocardial fibrosis, including left ventricular hypertrophy (LVH).
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