发明授权
- 专利标题: Piperazine derivatives
- 专利标题(中): 哌嗪衍生物
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申请号: US348176申请日: 1994-11-28
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公开(公告)号: US5670505A公开(公告)日: 1997-09-23
- 发明人: Masaaki Matsuo , Daijiro Hagiwara , Takashi Manabe , Nobukiyo Konishi , Shinji Shigenaga , Kenji Murano , Hiroshi Matsuda , Hiroshi Miyake
- 申请人: Masaaki Matsuo , Daijiro Hagiwara , Takashi Manabe , Nobukiyo Konishi , Shinji Shigenaga , Kenji Murano , Hiroshi Matsuda , Hiroshi Miyake
- 申请人地址: JPX Osaka
- 专利权人: Fujisawa Pharmaceutical Co., Ltd.
- 当前专利权人: Fujisawa Pharmaceutical Co., Ltd.
- 当前专利权人地址: JPX Osaka
- 优先权: GBX9324479 19931129; GBX9402010 19940202; GBX9412708 19940624
- 主分类号: A61K31/495
- IPC分类号: A61K31/495 ; A61K31/496 ; A61K31/55 ; A61P9/00 ; A61P11/00 ; A61P11/08 ; A61P17/00 ; A61P25/04 ; A61P25/06 ; A61P27/02 ; A61P27/14 ; A61P27/16 ; A61P29/00 ; A61P37/08 ; A61P43/00 ; C07D241/04 ; C07D401/06 ; C07D401/12 ; C07D401/14 ; C07D403/06 ; C07D403/14 ; C07D405/06 ; C07D405/14 ; C07D409/06 ; C07D417/06 ; C07D417/14
摘要:
A piperazine compound of the formula: ##STR1## wherein: X is carbonyl or sulfonyl; Y is a direct bond or lower alkylene; and R.sub.1, R.sub.2, R.sub.3, R.sub.4 are as defined herein. The compounds are advantageously used as Tachykinin antagonists in the treatment of respiratory diseases, ophthalmic diseases and inflammatory diseases, for example.
公开/授权文献
- US4442276A Process for polymerizing or copolymerizing olefins 公开/授权日:1984-04-10