发明授权
- 专利标题： Contrast agents comprising gas-containing or gas-generating polymer microparticles or microballoons
- 专利标题（中）： 造影剂包括含气体或产生气体的聚合物微粒或微球
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申请号： US301002申请日： 1994-09-06
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公开(公告)号： US5674468A公开(公告)日： 1997-10-07
- 发明人: Jo Klaveness , Pal Rongved , Jan Solberg , Per Strande , Unni Nordby Wiggen , Keith Redford
- 申请人： Jo Klaveness , Pal Rongved , Jan Solberg , Per Strande , Unni Nordby Wiggen , Keith Redford
- 申请人地址： NOX Oslo
- 专利权人： Nycomed Imaging AS
- 当前专利权人： Nycomed Imaging AS
- 当前专利权人地址： NOX Oslo
- 优先权： GBX9204918 19920306; GBX9204920 19920306
- 主分类号： A61K49/18
- IPC分类号： A61K49/18 ; A61K49/22 ; C08G63/00 ; A61K9/14
摘要：
Contrast agents comprising gas-containing or gas-generating polymer microparticles and/or microballoons, in which the polymer is a biodegradable polymer containing units of formula --(O).sub.m --CO--O--C(R.sup.1 R.sup.2)--O--CO--(O).sub.n -- (wherein R.sup.1 and R.sup.2 each represent hydrogen or a carbon-attached monovalent organic group or together form a carbon-attached divalent organic group, and m and n are each independently zero or one) may be used in diagnostic applications such as ultrasound and MR imaging.
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