发明授权
- 专利标题： Process for preparing aromatic amide compound
- 专利标题（中）： 制备芳香族酰胺化合物的方法
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申请号： US673441申请日： 1996-06-28
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公开(公告)号： US5675036A公开(公告)日： 1997-10-07
- 发明人: Etsuko Fukuda , Atsushi Furutani , Hideki Ushio , Hirokazu Murata
- 申请人： Etsuko Fukuda , Atsushi Furutani , Hideki Ushio , Hirokazu Murata
- 申请人地址： JPX Osaka
- 专利权人： Sumitomo Chemical Company, Limited
- 当前专利权人： Sumitomo Chemical Company, Limited
- 当前专利权人地址： JPX Osaka
- 优先权： JPX7-163551 19950629
- 主分类号： C07C67/31
- IPC分类号： C07C67/31 ; C07C231/02
摘要：
3-�4-(4-Phenyl-1-butoxy)benzoyl!amino-2-hydroxyacetophenone is prepared by reacting a benzoate ester with a halobutylbenzene in the presence of a basic compound and an aprotic polar compound in an aromatic hydrocarbon solvent to obtain a corresponding ether, alkali hydrolyzing the ether in an aromatic hydrocarbon solvent and precipitating a hydrolysate with an acid to obtain 4-(4-phenyl-1-butoxy)benzoic acid, reacting a halogenating agent with this benzoic acid derivative in an aromatic hydrocarbon solvent to obtain an acid halide, and reacting the acid halide in an aromatic hydrocarbon solvent with a corresponding aromatic amine.
公开/授权文献
- US4016254A Pharmaceutical formulations 公开/授权日：1977-04-05