A rotational ablation device for use in medical applications which are designed to reduce lesions, particularly vein-graft lesions, within blood vessels, the device includes a distal balloon located at the end of a guide wire, a proximal balloon having a cuff surrounding a guide catheter, an inflation lumen for use in inflating a distal balloon on the guide catheter, one or more rotating burrs used in conjunction with a helical drive system surrounding the guidewire; a suction system to remove ablated lesion material; and a control console to provide for the necessary control of the various systems of the device.