发明授权
US5684137A S.sub.3 N chelating compounds for the radiolabeling of ligands,
anti-ligands or other proteins
失效
用于放射性标记配体,抗配体或其他蛋白质的S3N螯合化合物
- 专利标题: S.sub.3 N chelating compounds for the radiolabeling of ligands, anti-ligands or other proteins
- 专利标题(中): 用于放射性标记配体,抗配体或其他蛋白质的S3N螯合化合物
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申请号: US393882申请日: 1995-02-22
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公开(公告)号: US5684137A公开(公告)日: 1997-11-04
- 发明人: Sudhakar Kasina , Linda M. Gustavson
- 申请人: Sudhakar Kasina , Linda M. Gustavson
- 申请人地址: WA Seattle
- 专利权人: NeoRx Corporation
- 当前专利权人: NeoRx Corporation
- 当前专利权人地址: WA Seattle
- 主分类号: A61K51/04
- IPC分类号: A61K51/04 ; C07D495/04 ; C07F13/00 ; G01N33/534 ; C07D473/00 ; C07K14/77
摘要:
Novel chelating compounds and the corresponding radionuclide metal chelates are useful for radiolabeling proteins such as antibodies, ligands such as biotin and anti-ligands such as streptavidin with radionuclide metals such as .sup.99m Tc, .sup.186 Re, and .sup.188 Re. The radiolabeled proteins, ligands and anti-ligands have diagnostic or therapeutic use, depending on the radionuclide metal chosen.
公开/授权文献
- US4940246A Arrow attachment 公开/授权日:1990-07-10
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