发明授权
- 专利标题: Detection of isoniazid resistent strains of M. tuberculosis
- 专利标题(中): 检测异烟肼耐药结核分枝杆菌菌株
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申请号: US228662申请日: 1994-04-18
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公开(公告)号: US5688639A公开(公告)日: 1997-11-18
- 发明人: Franklin R. Cockerill , Bruce C. Kline , James R. Uhl
- 申请人: Franklin R. Cockerill , Bruce C. Kline , James R. Uhl
- 申请人地址: MN Rochester
- 专利权人: Mayo Foundation for Medical Education and Research
- 当前专利权人: Mayo Foundation for Medical Education and Research
- 当前专利权人地址: MN Rochester
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68 ; C07H21/02 ; C07H21/04 ; C12P19/34
摘要:
A method for determining the susceptibility of a strain of M. tuberculosis to isoniazid is provided comprising employing the techniques of restriction length polymorphism analysis to determine whether or not the DNA of said strain has an NciI-MspI restriction site at the codon corresponding to codon 463 of an M. tuberculosis katG gene consensus sequence.
公开/授权文献
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