发明授权
- 专利标题： APC antibodies
- 专利标题（中）： APC抗体
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申请号： US452654申请日： 1995-05-25
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公开(公告)号： US5691454A公开(公告)日： 1997-11-25
- 发明人: Hans Albertsen , Rakesh Anand , Mary Carlson , Joanna Groden , Philip John Hedge , Geoff Joslyn , Kenneth Kinzler , Alexander Fred Markham , Yusuke Nakamura , Andrew Thliveris , Bert Vogelstein , Raymond L. White
- 申请人： Hans Albertsen , Rakesh Anand , Mary Carlson , Joanna Groden , Philip John Hedge , Geoff Joslyn , Kenneth Kinzler , Alexander Fred Markham , Yusuke Nakamura , Andrew Thliveris , Bert Vogelstein , Raymond L. White
- 申请人地址： MD Baltimore UT Salt Lake City GB2 London JPX Tokyo
- 专利权人： The Johns Hopkins University,University of Utah,the Cancer Institute,Imperial Chemical Industries PLC
- 当前专利权人： The Johns Hopkins University,University of Utah,the Cancer Institute,Imperial Chemical Industries PLC
- 当前专利权人地址： MD Baltimore UT Salt Lake City GB2 London JPX Tokyo
- 优先权： GBX9100962 19910116; GBX9100963 19910116; GBX9100974 19910116; GBX9100975 19910116
- 主分类号： C07K14/47
- IPC分类号： C07K14/47 ; C07K14/82 ; C07K16/32 ; C12N5/12 ; C12N15/12 ; C12Q1/68
摘要：
A human gene termed APC is disclosed. Methods and kits are provided for assessing mutations of the APC gene in human tissues and body samples. APC mutations are found in familial adenomatous polyposis patients as well as in sporadic colorectal cancer patients. APC is expressed in most normal tissues. These results suggest that APC is a tumor suppressor.
公开/授权文献
- US4995199A Magnetic tape cassette having improved guide pole structure 公开/授权日：1991-02-26
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