A column for low pressure-high speed liquid chromatography, including a column body being made of a transparent or translucent plastic and having a column chamber, said column body having one end opened and the other provided with an outflow opening, a pair of upstream and downstream filters for shutting a granular filler inside said column chamber, and a head portion being made of a plastic and detachably being fitted to said one open end of the column body and having an inflow through opening communicating with interior of said column body. A column device includes the column and a method for using the column device are also disclosed for low pressure-high speed liquid chromatography.