Invention Grant
- Patent Title: Methods of making transgenic animals producing oligosaccharides and glycoproteins
- Patent Title (中): 制备转基因动物产生寡糖和糖蛋白的方法
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Application No.: US434151Application Date: 1995-05-02
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Publication No.: US5700671APublication Date: 1997-12-23
- Inventor: Pedro Antonio Prieto , David Fletcher Smith , Richard Dale Cummings , John Joseph Kopchick , Pradip Mukerji , Kelley Wilson Moremen , James Michael Pierce
- Applicant: Pedro Antonio Prieto , David Fletcher Smith , Richard Dale Cummings , John Joseph Kopchick , Pradip Mukerji , Kelley Wilson Moremen , James Michael Pierce
- Applicant Address: IL Abbott Park
- Assignee: Abbott Laboratories
- Current Assignee: Abbott Laboratories
- Current Assignee Address: IL Abbott Park
- Main IPC: A01K67/027
- IPC: A01K67/027 ; C12N5/10 ; C12N9/10 ; C12N9/14 ; C12N15/09 ; C12N15/85 ; C12R1/91 ; C12N15/00 ; C12P21/06 ; C12Q1/68
Abstract:
The invention relates to transgenic non-human mammals characterized in that the genome of said mammals contain at least one heterologous gene encoding for the production of heterologous catalytic entity selected from the group consisting of enzymes and antibodies, and wherein said catalytic entity produces a second heterologous product in the milk of said mammal. Especially useful in the practice of the invention are human glycosyltransferases and transgenic sheep, goats and cows. The heterologous product includes oligosaccharides and glycoconjugates.
Public/Granted literature
- US4960609A Process for bonding lubricant to a thin film magnetic recording disk Public/Granted day:1990-10-02
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