Invention Grant
- Patent Title: Process and solvate of 2-methyl-thieno-benzodiazepine
- Patent Title (中): 2-甲基 - 噻吩并苯并二氮杂卓的方法和溶剂化物
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Application No.: US586431Application Date: 1996-01-16
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Publication No.: US5703232APublication Date: 1997-12-30
- Inventor: Charles A. Bunnell , Terrence Michael Hotten , Samuel D. Larsen , David Edward Tupper
- Applicant: Charles A. Bunnell , Terrence Michael Hotten , Samuel D. Larsen , David Edward Tupper
- Applicant Address: IN Indianapolis
- Assignee: Eli Lilly and Company
- Current Assignee: Eli Lilly and Company
- Current Assignee Address: IN Indianapolis
- Main IPC: C07D495/04
- IPC: C07D495/04 ; C07D243/10
Abstract:
The invention provides lower alcohol solvates of 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno�2,3-b!�1,5!benzodiazepine (olanzapine) and a process for making such lower alcohol solvates of olanzapine. The invention provides a method for using such solvates of olanzapine to prepare substantially pure anhydrous Form I 2-methyl-thieno-benzodiazepine.
Public/Granted literature
- US5067644A Rack protective device Public/Granted day:1991-11-26
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