发明授权
- 专利标题: Magnetic resonance imaging agents for the detection of physiological agents
- 专利标题(中): 用于检测生理剂的磁共振成像剂
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申请号: US486968申请日: 1995-06-07
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公开(公告)号: US5707605A公开(公告)日: 1998-01-13
- 发明人: Thomas Meade , Scott Fraser , Russell Jacobs
- 申请人: Thomas Meade , Scott Fraser , Russell Jacobs
- 申请人地址: AZ Tucson
- 专利权人: Research Corporation Technologies
- 当前专利权人: Research Corporation Technologies
- 当前专利权人地址: AZ Tucson
- 主分类号: A61K49/00
- IPC分类号: A61K49/00 ; A61K49/06 ; A61K49/08 ; G01N31/00 ; G01N33/48
摘要:
The invention relates to magnetic resonance imaging agents comprising a paramagnetic metal ion bound to a complex wherein said complex comprises a chelator and a blocking moiety convalently attached to said chelator which binds in at least a first coordination site of said metal ion and which is capable of interacting with a target substance such that the exchange of water in at least said first coordination site is increased.
公开/授权文献
- US3968383A Noise limiter 公开/授权日:1976-07-06
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