发明授权
US5708034A Substituted sulfonimidamides, processes for their preparation, their use
as a medicament or diagnostic, and medicament comprising them
失效
取代的磺酰亚胺酰胺，其制备方法，它们作为药物或诊断剂的用途，以及包含它们的药物
- 专利标题： Substituted sulfonimidamides, processes for their preparation, their use as a medicament or diagnostic, and medicament comprising them
- 专利标题（中）： 取代的磺酰亚胺酰胺，其制备方法，它们作为药物或诊断剂的用途，以及包含它们的药物
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申请号： US740634申请日： 1996-10-31
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公开(公告)号： US5708034A公开(公告)日： 1998-01-13
- 发明人: Heinz-Werner Kleemann , Joachim Brendel , Jan-Robert Schwark , Andreas Weichert , Hans Jochen Lang , Udo Albus , Wolfgang Scholz
- 申请人： Heinz-Werner Kleemann , Joachim Brendel , Jan-Robert Schwark , Andreas Weichert , Hans Jochen Lang , Udo Albus , Wolfgang Scholz
- 申请人地址： DEX Frankfurt am Main
- 专利权人： Hoechst Aktiengesellschaft
- 当前专利权人： Hoechst Aktiengesellschaft
- 当前专利权人地址： DEX Frankfurt am Main
- 优先权： DEX19540995.7 19951103
- 主分类号： A61K31/165
- IPC分类号： A61K31/165 ; A61K31/18 ; A61P1/16 ; A61P3/08 ; A61P9/04 ; A61P9/08 ; A61P9/10 ; A61P11/00 ; A61P13/02 ; A61P15/00 ; A61P35/00 ; A61P41/00 ; A61P43/00 ; C07C279/18 ; C07C313/02 ; C07C313/06 ; C07C381/10 ; A61K31/275 ; A61K31/21
摘要：
Substituted sulfonimidamides, processes for their preparation, their use as a medicament or diagnostic, and medicament comprising them Sulfonimidamides of the formula I ##STR1## in which at least one of the three substituents R(1), R(2) and R(3) is a benzoylguanidine, and in which the other substituents have the meanings indicated in the claims, are outstandingly suitable as medicaments having action on the cardiovascular system; that is as antiarrhythmic pharmaceuticals having a cardioprotective component as well as for treating ischemically induced damage; also in operative interventions, such as organ transplantation.
公开/授权文献
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