发明授权
US5714578A Human derived monocyte attracting purified protein product useful in a
method of treating infection and neoplasms in a human body
失效
人源性单核细胞吸引纯化的蛋白质产物，可用于治疗人体感染和赘生物的方法
- 专利标题： Human derived monocyte attracting purified protein product useful in a method of treating infection and neoplasms in a human body
- 专利标题（中）： 人源性单核细胞吸引纯化的蛋白质产物，可用于治疗人体感染和赘生物的方法
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申请号： US466280申请日： 1995-06-06
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公开(公告)号： US5714578A公开(公告)日： 1998-02-03
- 发明人: Teizo Yoshimura , Elizabeth A. Robinson , Ettore Appella , Edward J. Leonard
- 申请人： Teizo Yoshimura , Elizabeth A. Robinson , Ettore Appella , Edward J. Leonard
- 申请人地址： DC Washington
- 专利权人： The United States of America as represented by the Department of Health and Human Services
- 当前专利权人： The United States of America as represented by the Department of Health and Human Services
- 当前专利权人地址： DC Washington
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; C07K14/52 ; C12N15/19 ; A61K38/17
摘要：
Pure peptide products, derived from either human glioma cell line U-105MG or human peripheral blood mononuclear leukocytes are provided; the products have a molecular mass of about 8,400 daltons, and the products exhibit optimal monocyte chemotactic activity at a concentration of 1 nM. Methods of treating infection and neoplasms in a human body with such peptides and monocyte chemoattractant products are additionally provided, as well as pharmaceutical compositions for the same.
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