发明授权
US5716989A Bicyclo�3.3.0!octane derivatives, process for their production and their
pharmaceutical use
失效
双环[3.3.0]辛烷衍生物，其生产工艺及其药物用途
- 专利标题： Bicyclo�3.3.0!octane derivatives, process for their production and their pharmaceutical use
- 专利标题（中）： 双环[3.3.0]辛烷衍生物，其生产工艺及其药物用途
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申请号： US777363申请日： 1991-11-27
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公开(公告)号： US5716989A公开(公告)日： 1998-02-10
- 发明人: Ulrich Klar , Hartmut Rehwinkel , Helmut Vorbruggen , Karl Heinz Thierauch , Peter Verhallen
- 申请人： Ulrich Klar , Hartmut Rehwinkel , Helmut Vorbruggen , Karl Heinz Thierauch , Peter Verhallen
- 申请人地址： DEX Berlin
- 专利权人： Schering Aktiengesellschaft
- 当前专利权人： Schering Aktiengesellschaft
- 当前专利权人地址： DEX Berlin
- 优先权： DEX4010355.2 19900328
- 主分类号： A61K31/335
- IPC分类号： A61K31/335 ; A61K31/357 ; A61K31/41 ; A61K31/42 ; A61K31/421 ; A61K31/44 ; A61K31/4427 ; A61K31/443 ; A61K31/47 ; A61K31/557 ; A61P9/00 ; A61P9/08 ; A61P9/10 ; A61P9/12 ; A61P11/08 ; C07C251/42 ; C07C281/10 ; C07C311/49 ; C07C335/40 ; C07C405/00 ; C07D257/04 ; C07D263/10 ; C07D263/14 ; C07D263/16 ; C07D263/22 ; C07D319/06 ; C07D401/12 ; C07D405/12 ; C07D413/12 ; C07D493/08 ; A61K31/21
摘要：
The invention relates to bicyclo�3.3.0!octane compounds of formula I, ##STR1## wherein the variable are defined in this specification, as well as their enantiomers, and their salts with physiologically compatible bases. .alpha.-, .beta.-, or .tau.-Cyclodextrin clathrates of the compounds and the compounds encapsulated with liposomes are also included. The invention is further directed to processes for production of the compounds and their pharmaceutical use.
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