A refrigerated centrifuge system. The system includes at least one thermoelectric cooler which is operatively connected to a centrifuge chamber by an egress conduit and an ingress conduit. In one embodiment the egress conduit carries away from the centrifuge to the thermoelectric cooler warm air where it is cooled by the thermoelectric cooler. The cooled air then returns to the centrifuge. In another embodiment the warm air in the centrifuge is first passed through a liquid heat exchanger whereby the warmed air transfers heat to a liquid which then is pumped through an egress conduit to a thermoelectric cooler where the liquid is cooled. The cooled liquid is then pumped back to the liquid heat exchanger through an ingress conduit.