发明授权
US5731306A Mercaptoacetylamido 1,3,4,5-tetrahydro-benzo�c!azepin-3-one disulfide
derivatives useful as inhibitors of enkephalinase and ace
失效
巯基乙酰氨基1,3,4,5-四氢 - 苯并[c]氮杂-3-酮二硫化物衍生物，可用作脑啡肽酶和ace的抑制剂
- 专利标题： Mercaptoacetylamido 1,3,4,5-tetrahydro-benzo�c!azepin-3-one disulfide derivatives useful as inhibitors of enkephalinase and ace
- 专利标题（中）： 巯基乙酰氨基1,3,4,5-四氢 - 苯并[c]氮杂-3-酮二硫化物衍生物，可用作脑啡肽酶和ace的抑制剂
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申请号： US673250申请日： 1996-06-26
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公开(公告)号： US5731306A公开(公告)日： 1998-03-24
- 发明人: Gary A. Flynn , Douglas W. Beight , Alan M. Warshawsky , Shujaath Mehdi , John F. French , John H. Kehne
- 申请人： Gary A. Flynn , Douglas W. Beight , Alan M. Warshawsky , Shujaath Mehdi , John F. French , John H. Kehne
- 专利权人： Flynn; Gary A.,Beight; Douglas W.,Warshawsky; Alan M.,Mehdi; Shujaath,French; John F.,Kehne; John H.
- 当前专利权人： Flynn; Gary A.,Beight; Douglas W.,Warshawsky; Alan M.,Mehdi; Shujaath,French; John F.,Kehne; John H.
- 主分类号： C12N9/99
- IPC分类号： C12N9/99 ; A61K38/00 ; A61K38/55 ; A61P1/04 ; A61P7/10 ; A61P9/00 ; A61P9/12 ; A61P25/00 ; A61P25/04 ; A61P43/00 ; C07K1/06 ; C07K5/06 ; C07K5/078 ; A61K31/55 ; C07D498/04
摘要：
The present invention relates to certain novel mercaptoacetylamido 1,3,4,5-tetrahydro-benzo�c!azepin-3-one disulfide derivatives of the formula ##STR1## useful as inhibitors of enkephalinase and of ACE.