发明授权
- 专利标题： Substituted benzenesulfonylureas and -thioureas, preparation processes and possible uses of pharmaceutical preparations based on these compounds
- 专利标题（中）： 取代的苯磺酰脲和硫脲，基于这些化合物的药物制剂的制备方法和可能的用途
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申请号： US705697申请日： 1996-08-30
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公开(公告)号： US5731341A公开(公告)日： 1998-03-24
- 发明人: Heinrich Englert , Dieter Mania , Jens Hartung , Heinz Gogelein , Joachim Kaiser , Uwe Gerlach
- 申请人： Heinrich Englert , Dieter Mania , Jens Hartung , Heinz Gogelein , Joachim Kaiser , Uwe Gerlach
- 申请人地址： DEX Frankfurt am Main
- 专利权人： Hoechst Aktiengesellschaft
- 当前专利权人： Hoechst Aktiengesellschaft
- 当前专利权人地址： DEX Frankfurt am Main
- 优先权： DEX4344957.3 19931230
- 主分类号： C07D207/38
- IPC分类号： C07D207/38 ; C07D521/00 ; A61K31/40 ; C07D209/46
摘要：
Described herein are substituted benzenesulfonylureas and -thioureas of the formula (I): ##STR1## useful in treatment of disturbances in cardiac rhythm and prevention of sudden cardiac death caused by arrythmia. The compounds of formula (I) can be used as antiarrythmics and are particularly suitable for those cases where arrhythmias are a consequence of a narrowing of a coronary vessel, such as angina pectoris or acute cardiac infarction.
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