发明授权
US5733914A Pyrido�2, 3-d!pyrimidines for inhibiting protein tyrosine kinase
mediated cellular proliferation
失效
吡啶并[2,3-d]嘧啶，用于抑制蛋白酪氨酸激酶介导的细胞增殖
- 专利标题： Pyrido�2, 3-d!pyrimidines for inhibiting protein tyrosine kinase mediated cellular proliferation
- 专利标题（中）： 吡啶并[2,3-d]嘧啶，用于抑制蛋白酪氨酸激酶介导的细胞增殖
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申请号： US611279申请日： 1996-04-03
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公开(公告)号： US5733914A公开(公告)日： 1998-03-31
- 发明人: Clifton John Blankley , Diane Harris Boschelli , Annette Marian Doherty , James Marino Hamby , Sylvester Klutchko , Robert Lee Panek
- 申请人： Clifton John Blankley , Diane Harris Boschelli , Annette Marian Doherty , James Marino Hamby , Sylvester Klutchko , Robert Lee Panek
- 申请人地址： NJ Morris Plains
- 专利权人： Warner-Lambert Company
- 当前专利权人： Warner-Lambert Company
- 当前专利权人地址： NJ Morris Plains
- 主分类号： C07D471/04
- IPC分类号： C07D471/04 ; A61K31/505 ; C07D487/02
摘要：
6-Aryl pyrido�2,3-d!pyrimidine 7-imines, 7-ones, and 7-thiones are inhibitors of protein tyrosine kinases, and are thus useful in treating cellular proliferation mediated thereby. The compounds are especially useful in treating cancer, atherosclerosis, restenosis, and psoriasis.
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