发明授权
- 专利标题: Substituted amino alcohol compounds
- 专利标题(中): 取代氨基醇化合物
-
申请号: US475721申请日: 1995-06-07
-
公开(公告)号: US5750575A公开(公告)日: 1998-05-12
- 发明人: J. Peter Klein , Gail E. Underiner , Anil M. Kumar
- 申请人: J. Peter Klein , Gail E. Underiner , Anil M. Kumar
- 申请人地址: WA Seattle
- 专利权人: Cell Therapeutics, Inc.
- 当前专利权人: Cell Therapeutics, Inc.
- 当前专利权人地址: WA Seattle
- 主分类号: A61K31/45
- IPC分类号: A61K31/45 ; A61K31/47 ; A61K31/513 ; A61K31/519 ; A61K31/522 ; C07C215/08 ; C07C215/56 ; C07C217/62 ; C07C217/64 ; C07C229/22 ; C07C233/36 ; C07C233/78 ; C07C233/91 ; C07D207/40 ; C07D207/404 ; C07D209/48 ; C07D211/76 ; C07D211/88 ; C07D217/24 ; C07D239/54 ; C07D239/90 ; C07D239/96 ; C07D295/13 ; C07D473/10 ; A61K31/165 ; A61K31/135 ; C07C215/20 ; C07C233/35
摘要:
Disclosed are compounds having a straight or branched aliphatic hydrocarbon structure of formula I: ##STR1## In formula I, n is an integer from one to four and m is an integer from four to twenty. Independently, R.sub.1 and R.sub.2 are hydrogen, a straight or branched chain alkyl, alkenyl or alkynyl of up to twenty carbon atoms in length or --(CH.sub.2).sub.w R.sub.5. If R.sub.1 or R.sub.2 is --(CH.sub.2).sub.w R.sub.5, w may be an integer from one to twenty and R.sub.5 may be an hydroxyl, halo, C.sub.1-8 alkoxyl group or a substituted or unsubstituted carbocycle or heterocycle. Alternatively, R.sub.1 and R.sub.2 may jointly form a substituted or unsubstituted, saturated or unsaturated heterocycle having from four to eight carbon atoms, N being a hetero atom of the resulting heterocyle. R.sub.3 may be either hydrogen or C.sub.1-3. In the compounds, a total sum of carbon atoms comprising R.sub.1 or R.sub.2, (CH.sub.2).sub.n and (CH.sub.2).sub.m does not exceed forty. R.sub.4 is a carbocycle comprising a substituted or unsubstituted ring system, the ring system having a single ring or two fused rings, a ring comprising from three to seven ring atoms. The disclosed compounds are effective agents to inhibit undesirable responses to cell stimuli.
公开/授权文献
- US5001836A Apparatus for boresighting a firearm 公开/授权日:1991-03-26
信息查询
IPC分类: