发明授权
- 专利标题： Carboxylic acid compound having condensed ring, salt thereof and pharmaceutical use thereof
- 专利标题（中）： 具有稠环的羧酸化合物及其盐及其药物用途
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申请号： US824541申请日： 1997-03-26
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公开(公告)号： US5753670A公开(公告)日： 1998-05-19
- 发明人: Shinichiro Ono , Tomohiro Yoshida , Atsuyuki Ashimori , Keigo Kosaka , Takehiro Okada , Kazuhiro Maeda , Masahiro Eda , Fumio Mori , Yoshihisa Inoue , Hajime Ebisu , Teruaki Imada , Ruriko Ikegawa , Feng Wang , Norifumi Nakamura
- 申请人： Shinichiro Ono , Tomohiro Yoshida , Atsuyuki Ashimori , Keigo Kosaka , Takehiro Okada , Kazuhiro Maeda , Masahiro Eda , Fumio Mori , Yoshihisa Inoue , Hajime Ebisu , Teruaki Imada , Ruriko Ikegawa , Feng Wang , Norifumi Nakamura
- 申请人地址： JPX Osaka
- 专利权人： The Green Cross Corporation
- 当前专利权人： The Green Cross Corporation
- 当前专利权人地址： JPX Osaka
- 优先权： JPX6-124092 19940606; JPX7-39974 19950228
- 主分类号： C07D209/42
- IPC分类号： C07D209/42 ; C07D307/84 ; C07D307/85 ; C07D333/62 ; C07D333/68 ; C07D491/04 ; C07D491/048 ; A61K31/55 ; A61K31/44 ; C07D471/02 ; C07D498/02
摘要：
A novel carboxylic acid compound having a condensed ring; which is represented by the formula (I) ##STR1## wherein each symbol is as defined in the specification, a pharmacologically acceptable salt thereof, a pharmaceutical composition thereof and pharmaceutical use thereof. The novel carboxylic acid compound having a condensed ring and pharmacologically acceptable salt thereof of the present invention have superior GPIIb/IIIa antagonism in mammals inclusive of human; can be administered orally; have long life in blood and low toxicity; and show less side-effects. Accordingly, they are extremely useful for the prophylaxis and treatment of thrombotic diseases and other diseases.
公开/授权文献
- US4769817A Concurrent fault simulation for logic designs 公开/授权日：1988-09-06
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