发明授权
- 专利标题： Cyclodextrin liposomes encapsulating pharmacologic compounds and methods for their use
- 专利标题（中）： 包封药物化合物的环糊精脂质体及其使用方法
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申请号： US535256申请日： 1995-12-21
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公开(公告)号： US5759573A公开(公告)日： 1998-06-02
- 发明人: Sinil Kim
- 申请人： Sinil Kim
- 申请人地址： CA San Diego
- 专利权人： DepoTech Corporation
- 当前专利权人： DepoTech Corporation
- 当前专利权人地址： CA San Diego
- 主分类号： A61K9/127
- IPC分类号： A61K9/127 ; A61K9/133 ; A61K47/40 ; A61K47/48
摘要：
Liposomes containing cyclodextrin in the encapsulated aqueous phase are useful for encapsulation of biologically active substances, especially those which are hydrophilic. The encapsulated cyclodextrin facilitates a slow, controlled release of pharmacologic compounds from the liposomes. The novel methods of the present invention allow the treatment of a variety of pathophysiological states by administering the cyclodextrin-containing liposomes encapsulating the pharmacologic compounds. The present invention also provides a novel method of extending the half life of a pharmacologic compound in an animal.
公开/授权文献
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