发明授权
- 专利标题: Phenoxyphenylacetic acid derivatives
- 专利标题(中): 苯氧基苯乙酸衍生物
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申请号: US507492申请日: 1995-11-08
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公开(公告)号: US5767310A公开(公告)日: 1998-06-16
- 发明人: Scott W. Bagley , Theodore P. Broten , Prasun K. Chakravarty , Daljit S. Dhanoa , Kenneth J. Fitch , William J. Greenlee , Nancy Jo Kevin , Douglas J. Pettibone , Ralph A. Rivero , James R. Tata , Thomas F. Walsh , David L. Williams, Jr.
- 申请人: Scott W. Bagley , Theodore P. Broten , Prasun K. Chakravarty , Daljit S. Dhanoa , Kenneth J. Fitch , William J. Greenlee , Nancy Jo Kevin , Douglas J. Pettibone , Ralph A. Rivero , James R. Tata , Thomas F. Walsh , David L. Williams, Jr.
- 申请人地址: NJ Rahway
- 专利权人: Merck & Co., Inc.
- 当前专利权人: Merck & Co., Inc.
- 当前专利权人地址: NJ Rahway
- 主分类号: C07C59/70
- IPC分类号: C07C59/70 ; C07C65/24 ; C07C311/51 ; C07D257/04 ; C07D317/60 ; C07D317/64 ; C07D319/18 ; C07D405/12 ; C07C59/40
摘要:
Phenoxyphenylacetic acids and derivatives of general structural formula (I) have endothelin antagonist activity and are useful in treating cardiovascular disorders, such as hypertension, postischemic renal failure, vasospasm, cerebral and cardiac ischemia, myocardial infarction, endoxic shock, benign prostatic hyperplasia, inflammatory diseases including Raynaud's disease and asthma.
公开/授权文献
- US5048093A Defect counting method and apparatus 公开/授权日:1991-09-10
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