发明授权
- 专利标题: 2-(1H) quinolinone compounds
- 专利标题(中): 2-(1H)喹啉酮化合物
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申请号: US889920申请日: 1997-07-10
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公开(公告)号: US5776949A公开(公告)日: 1998-07-07
- 发明人: Alex Cordi , Patrice Desos , Jean Lepagnol , Philippe Morain , Pierre Lestage
- 申请人: Alex Cordi , Patrice Desos , Jean Lepagnol , Philippe Morain , Pierre Lestage
- 申请人地址: FRX Courbevoie
- 专利权人: Adir et Compagnie
- 当前专利权人: Adir et Compagnie
- 当前专利权人地址: FRX Courbevoie
- 主分类号: A61K31/47
- IPC分类号: A61K31/47 ; A61P9/00 ; A61P25/00 ; A61P25/08 ; A61P25/18 ; A61P25/28 ; A61P43/00 ; C07D215/36 ; C07D401/04 ; C07D471/04 ; C07D521/00
摘要:
A compound of formula (I): ##STR1## in which: R.sub.1, R.sub.2, R.sub.3, which are identical or different, represent hydrogen, halogen, alkyl, nitro, cyano, aminosulfonyl, imidazolyl, or pyrrolyl, or alternatively, when two of them are situated on adjacent carbons, may form with the carbon atoms to which they are attached a benzene ring on C.sub.3 -C.sub.7 cyloalkyl R.sub.4 represents hydroxyl, alkoxy, phenoxy, or amino, their isomers as well as their addition salts with a pharmaceutically-acceptable base, and medicinal products containing the same which are useful as inhibitors of the the pathological phenomena linked to hyperactivation of the neurotransmission pathways by the excitatory amino acids.
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