In a method for driving an active matrix type liquid crystal display device having a liquid crystal panel having the structure that a set of liquid crystal layers and two-terminal active layers are connected in series between a set of column electrodes and a set of row electrodes, a display operation being carried out by applying a difference signal between each column electrode and each row electrode, the difference signal is set so as to have a voltage having an inverse characteristic to the I-V characteristic of the two-terminal active element and is applied between the column and row electrodes to thereby depress occurrence of flicker. In addition, within a period except for a selection period for which an actual display operation is carried out in the liquid crystal panel, the difference signal having amplitude voltage equal to or above the maximum amplitude voltage set for the display operation is applied between the column and row electrode sets for a predetermined period to thereby prevent degradation of display quality due to the shift characteristic of the two-terminal active element which has been driven, and due to the asymmetry of the voltage-current characteristic of the two-terminal active element between the positive and negative polarity regions thereof.