发明授权
US5792778A 2-substituted aryl pyrroles, compositions containing such compounds and
methods of use
失效
2-取代的芳基吡咯，含有这些化合物的组合物和使用方法
- 专利标题： 2-substituted aryl pyrroles, compositions containing such compounds and methods of use
- 专利标题（中）： 2-取代的芳基吡咯，含有这些化合物的组合物和使用方法
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申请号： US694008申请日： 1996-08-08
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公开(公告)号： US5792778A公开(公告)日： 1998-08-11
- 发明人: Stephen E. de Laszlo , Nigel J. Liverton , Gerald S. Ponticello , Harold G. Selnick , Nathan B. Mantlo
- 申请人： Stephen E. de Laszlo , Nigel J. Liverton , Gerald S. Ponticello , Harold G. Selnick , Nathan B. Mantlo
- 申请人地址： NJ Rahway
- 专利权人： Merck & Co., Inc.
- 当前专利权人： Merck & Co., Inc.
- 当前专利权人地址： NJ Rahway
- 主分类号： C07D401/04
- IPC分类号： C07D401/04 ; C07D401/14 ; C07D403/04 ; A61K31/40 ; A61K31/44 ; A61K31/445 ; C07D207/325 ; C07D213/06 ; C07D295/06 ; C07D213/33
摘要：
The present invention addresses 2-substituted aryl pyrroles, as well as compositions containing such compounds and methods of treatment. Cytokine mediated diseases refers to diseases or conditions in which excessive or unregulated production or activity of one or more cytokines occurs. Interleukin-1 (IL-1), Interleukin-6 (IL-6), Interleukin-8 (IL-8) and Tumor Necrosis Factor (TNF) are cytokines which are involved.