发明授权
- 专利标题: Method and compositions for inhibiting protein kinases
- 专利标题(中): 抑制蛋白激酶的方法和组合物
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申请号: US332597申请日: 1994-10-28
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公开(公告)号: US5795910A公开(公告)日: 1998-08-18
- 发明人: Neill A. Giese , Nathalie Lokker
- 申请人: Neill A. Giese , Nathalie Lokker
- 申请人地址: CA So. San Francisco
- 专利权人: Cor Therapeutics, Inc.
- 当前专利权人: Cor Therapeutics, Inc.
- 当前专利权人地址: CA So. San Francisco
- 主分类号: C12N9/99
- IPC分类号: C12N9/99 ; A61K31/365 ; A61K31/366 ; A61P35/02 ; C07D313/00 ; A61K31/335
摘要:
A method for selectively inhibiting a kinase is disclosed, which comprises contacting a composition containing a kinase with a molecule of the formula ##STR1## wherein R.sub.1 is H, lower alkyl, or lower alkanoyl; R.sub.2 is H, lower alkyl, or lower alkanoyl; R.sub.3 and R.sub.4 together represent a cis double bond or --O-- or each of R.sub.3 and R.sub.4 independently represents H or OR; R.sub.5 is .dbd.O, .dbd.S, or --H, --OR; R.sub.6 and R.sub.7 together represent a double bond or --O-- or each of R.sub.6 and R.sub.7 independently represents H or OR; R.sub.4 and R together represent a double bond or --O-- or each of R.sub.8 and R.sub.9 independently represents H or OR; and each R independently represents H, lower alkyl, or lower alkanoyl.
公开/授权文献
- US6046958A Latching wordline driver for multi-bank memory 公开/授权日:2000-04-04
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