发明授权
- 专利标题: Quinoline carboxanides and their therapeutic use
- 专利标题(中): 喹啉羧酰胺及其治疗用途
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申请号: US859508申请日: 1997-05-20
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公开(公告)号: US5804588A公开(公告)日: 1998-09-08
- 发明人: Hazel Joan Dyke , John Gary Montana , Christopher Lowe , Hannah Jayne Kendall , Verity Margaret Sabin
- 申请人: Hazel Joan Dyke , John Gary Montana , Christopher Lowe , Hannah Jayne Kendall , Verity Margaret Sabin
- 申请人地址: GBX
- 专利权人: Chiroscience Limited
- 当前专利权人: Chiroscience Limited
- 当前专利权人地址: GBX
- 优先权: GBX9610506 19960520; GBX9623234 19961107; GBX9626883 19961224; GBX9708072 19970422
- 主分类号: C07D215/26
- IPC分类号: C07D215/26 ; A61K31/00 ; A61K31/47 ; A61K31/472 ; A61K31/4725 ; A61K45/06 ; A61P43/00 ; C07D215/48 ; C07D401/12 ; C07D401/14 ; C07D417/12 ; C07D215/00
摘要:
The subject invention concerns novel compounds of the general formula (i) ##STR1## that are useful in treating disease states, such as those states associated with proteins that mediate cellular activity. The compounds of the subject invention can be used, for example, to inhibit tumor necrosis factor and/or phosphodiesterase IV, The subject invention also concerns methods for treating disease states using the compounds of the invention.
公开/授权文献
- US4127997A Rolling mill stand 公开/授权日:1978-12-05
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