发明授权
US5807721A Compound FO-1289, process of production with aspergillus and strain
失效
复合FO-1289，用曲霉菌和菌株生产的方法
- 专利标题： Compound FO-1289, process of production with aspergillus and strain
- 专利标题（中）： 复合FO-1289，用曲霉菌和菌株生产的方法
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申请号： US567066申请日： 1995-12-04
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公开(公告)号： US5807721A公开(公告)日： 1998-09-15
- 发明人: Satoshi Omura , Hiroshi Tomoda , Rokuro Masuma
- 申请人： Satoshi Omura , Hiroshi Tomoda , Rokuro Masuma
- 申请人地址： JPX Tokyo
- 专利权人： The Kitasato Institute
- 当前专利权人： The Kitasato Institute
- 当前专利权人地址： JPX Tokyo
- 优先权： JPX4-284759 19921022; JPX5-035261 19930224
- 主分类号： A61K31/44
- IPC分类号： A61K31/44 ; A61P3/06 ; C07D321/12 ; C07D493/04 ; C12N9/99 ; C12P17/18 ; C12R1/66 ; C12N1/14
摘要：
A FO-1289 substance of the formula ##STR1## wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are hydrogen or acyl. A process for the production thereof comprises culturing the novel microorganism Aspergillus sp. FO-1289 FERM BP-4242 in a nutrient medium, accumulating the FO-1289 substance thus produced in the medium, and isolating the FO-1289 substance therefrom. Particular species of the FO-1289 substance comprise FO-1289A, in which R.sub.1, R.sub.2 and R.sub.3 are acetyl and R.sub.4 is hydrogen; FO-1289B, wherein R.sub.1 is propionyl, R.sub.2 and R.sub.3 are acetyl and R.sub.4 is hydrogen; FO-1289C, wherein R.sub.1 and R.sub.3 are acetyl, R.sub.2 is propionyl and R.sub.4 is hydrogen; and FO-1289D, wherein R.sub.1 and R.sub.2 are acetyl, R.sub.3 is propionyl and R.sub.4 is hydrogen.
公开/授权文献
- US5209970A Magnetic recording media 公开/授权日：1993-05-11