发明授权
US5807989A Methods for treatment or diagnosis of diseases or disorders associated
with an APB domain
失效
用于治疗或诊断与APB结构域相关的疾病或病症的方法
- 专利标题： Methods for treatment or diagnosis of diseases or disorders associated with an APB domain
- 专利标题（中）： 用于治疗或诊断与APB结构域相关的疾病或病症的方法
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申请号： US363215申请日： 1994-12-23
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公开(公告)号： US5807989A公开(公告)日： 1998-09-15
- 发明人: Benjamin Lewis Margolis , Joseph Schlessinger , Vijay Yajnik
- 申请人： Benjamin Lewis Margolis , Joseph Schlessinger , Vijay Yajnik
- 申请人地址： NY New York
- 专利权人： New York University
- 当前专利权人： New York University
- 当前专利权人地址： NY New York
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; C07K14/71 ; C07K4/12 ; C07K5/00
摘要：
The present invention concerns methods for diagnosis and treatment of diseases or disorders characterized by abnormal cellular signal transduction involving a newly identified region, herein termed the "APB domain." APB domain binding between proteins is believed to play an important role in signal transduction pathways and, thereby, influence cellular events. Thus, APB mediated activity plays a role in signal transduction pathways and agents modulating APB mediated activity can be used to treat diseases or disorders involving proteins containing APB domains.
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