发明授权
US5811241A Method for preparing and identifying N-substitued 1,4-piperazines and
N-substituted 1,4-piperazinediones
失效
制备和鉴定N-取代的1,4-哌嗪和N-取代的1,4-哌嗪二酮的方法
- 专利标题: Method for preparing and identifying N-substitued 1,4-piperazines and N-substituted 1,4-piperazinediones
- 专利标题(中): 制备和鉴定N-取代的1,4-哌嗪和N-取代的1,4-哌嗪二酮的方法
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申请号: US527407申请日: 1995-09-13
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公开(公告)号: US5811241A公开(公告)日: 1998-09-22
- 发明人: Val S. Goodfellow , Donald A. McLeod , James Ivan Gerrity , Christopher P. Laudeman , Michael R. Burkard
- 申请人: Val S. Goodfellow , Donald A. McLeod , James Ivan Gerrity , Christopher P. Laudeman , Michael R. Burkard
- 申请人地址: CO Denver
- 专利权人: Cortech, Inc.
- 当前专利权人: Cortech, Inc.
- 当前专利权人地址: CO Denver
- 主分类号: C07D241/08
- IPC分类号: C07D241/08 ; C07D295/02 ; G01N33/53 ; G01N33/543 ; G01N33/566
摘要:
The invention provides a method of synthesizing N-substituted 1,4-piperazines and N-substituted 1,4-piperazinediones. The invention also provides a method for synthesing combinatorial libraries of piperazine derivatives which can be assayed for biological activity in pre-specified ligand binding or enzymatic activity screens.
公开/授权文献
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