发明授权
- 专利标题： Melanin production by streptomyces
- 专利标题（中）： 黑色素生成由链霉菌
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申请号： US404384申请日： 1995-03-14
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公开(公告)号： US5814495A公开(公告)日： 1998-09-29
- 发明人: Guy della-Cioppa , Stephen J. Garger, Jr. , Genadie G. Sverlow , Thomas H. Turpen , Laurence K. Grill , Miles R. Chedekal
- 申请人： Guy della-Cioppa , Stephen J. Garger, Jr. , Genadie G. Sverlow , Thomas H. Turpen , Laurence K. Grill , Miles R. Chedekal
- 申请人地址： CA Vacaville
- 专利权人： Biosource Technologies, Inc.
- 当前专利权人： Biosource Technologies, Inc.
- 当前专利权人地址： CA Vacaville
- 主分类号： C07K2/00
- IPC分类号： C07K2/00 ; C07K14/36 ; C12N9/02 ; C12P17/00 ; C12P17/14 ; A61K7/44
摘要：
The present invention is directed to a process for producing melanins, their precursors and their analoges, hereinafter referred to generically as melanins. According to the invention, melanins are produced in amounts greater than about 3.3 grams wet weight per liter of growth medium. The enhanced production of melanin can be achieved by manipulating the constituents of the growth medium, and/or attenuating fermentations conditions, and/or by genetically engineering microorganisms to produce melanins, and/or mutating the microorganisms.
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