发明授权
- 专利标题: Tetracyclic condensed heterocyclic compounds their production, and use
- 专利标题(中): 四环稠合杂环化合物的生产和使用
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申请号: US681911申请日: 1996-07-30
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公开(公告)号: US5814642A公开(公告)日: 1998-09-29
- 发明人: Giichi Goto , Yuji Ishihara , Masaomi Miyamoto
- 申请人: Giichi Goto , Yuji Ishihara , Masaomi Miyamoto
- 申请人地址: JPX Osaka
- 专利权人: Takeda Chemical Industries, Ltd.
- 当前专利权人: Takeda Chemical Industries, Ltd.
- 当前专利权人地址: JPX Osaka
- 优先权: JPX5-299799 19931130; JPX6-055984 19940325
- 主分类号: C07D471/06
- IPC分类号: C07D471/06 ; C07D487/04 ; C07D221/18 ; A61K31/395 ; A61K31/44 ; C07D401/02
摘要:
A novel compound of the formula ##STR1## wherein Ar represents a tetracyclic fused heterocyclic group which may be substituted; R.sup.1 represents H or a hydrocarbon group which may be substituted; Y represents an amino acid or nitrogen-containing saturated heterocyclic group which may be substituted, its salt, inhibiting excellent cholinesterase inhibitory activity and monoamine uptake inhibitory activity, thus being useful as therapeutic and/or prophylactic medicaments of senile dementia.
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