发明授权
- 专利标题: Regulated apoptosis
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申请号: US292597申请日: 1994-08-18
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公开(公告)号: US5834266A公开(公告)日: 1998-11-10
- 发明人: Gerald R. Crabtree , Stuart L. Schreiber , David M. Spencer , Thomas J. Wandless , Peter Belshaw
- 申请人: Gerald R. Crabtree , Stuart L. Schreiber , David M. Spencer , Thomas J. Wandless , Peter Belshaw
- 申请人地址: MA Cambridge CA Stanford
- 专利权人: President & Fellows of Harvard College,Board of Trustees of Leland Stanford Jr. University
- 当前专利权人: President & Fellows of Harvard College,Board of Trustees of Leland Stanford Jr. University
- 当前专利权人地址: MA Cambridge CA Stanford
- 主分类号: A61K38/00
- IPC分类号: A61K38/00 ; A61K47/48 ; A61K48/00 ; A61P43/00 ; C07D498/18 ; C07F5/02 ; C07H19/01 ; C07K7/64 ; C07K14/395 ; C07K14/705 ; C07K14/71 ; C07K14/715 ; C07K14/725 ; C12N15/62 ; C12N15/63 ; C12P15/00 ; C12P17/18 ; C12N5/10 ; C12N15/79
摘要:
We have developed a general procedure for the regulated (inducible) dimerization or oligomerization of intracellular proteins and disclose methods and materials for using that procedure to regulatably initiate cell-specific apoptosis (programmed cell death) in genetically engineered cells.
公开/授权文献
- US5039732A Water-dispersable air-drying coatings 公开/授权日:1991-08-13