发明授权
US5840936A Aminosterol compounds useful as inhibitors of the sodium/proton
exchanger (NHE)
失效
可用作钠/质子交换剂（NHE）抑制剂的氨基甾醇化合物
- 专利标题： Aminosterol compounds useful as inhibitors of the sodium/proton exchanger (NHE)
- 专利标题（中）： 可用作钠/质子交换剂（NHE）抑制剂的氨基甾醇化合物
-
申请号： US475572申请日： 1995-06-07
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公开(公告)号： US5840936A公开(公告)日： 1998-11-24
- 发明人: Michael Zasloff , Ann Shinnar , Meena Rao , William Kinney
- 申请人： Michael Zasloff , Ann Shinnar , Meena Rao , William Kinney
- 申请人地址： PA Plymouth Meeting
- 专利权人： Magainin Pharmaceuticals Inc.
- 当前专利权人： Magainin Pharmaceuticals Inc.
- 当前专利权人地址： PA Plymouth Meeting
- 主分类号： C07J41/00
- IPC分类号： C07J41/00 ; G01N33/50 ; C07C305/12
摘要：
Aminosterol compounds are described that are useful as inhibitors of the sodium/proton exchanger (NHE). Methods of using such aminosterols compounds are also enclosed, including those employing compounds that are inhibitors of a spectrum of NHEs as well as those using compounds that are inhibitors of only one specific NHE. Advantageous screening techniques and assays for evaluating a compound's therapeutic activity are also disclosed.
公开/授权文献
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