发明授权
US5854070A Murine and humanizer 23F2G antibodies and cell lines expressing said
antibodies
失效
鼠和人源化23F2G抗体和表达所述抗体的细胞系
- 专利标题: Murine and humanizer 23F2G antibodies and cell lines expressing said antibodies
- 专利标题(中): 鼠和人源化23F2G抗体和表达所述抗体的细胞系
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申请号: US785571申请日: 1997-01-21
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公开(公告)号: US5854070A公开(公告)日: 1998-12-29
- 发明人: Lynn M. Rose
- 申请人: Lynn M. Rose
- 申请人地址: WA Bothell WA Seattle
- 专利权人: ICOS Corporation,Board of Regents of the University of Washington
- 当前专利权人: ICOS Corporation,Board of Regents of the University of Washington
- 当前专利权人地址: WA Bothell WA Seattle
- 主分类号: A61K38/00
- IPC分类号: A61K38/00 ; C07K16/28 ; C07K16/18 ; C12N5/12
摘要:
Disclosed are methods for the alleviation of symptoms associated with inflammatory disease states, and more particularly to the inhibition of inflammatory processes associated with the multiple sclerosis disease, by administering a pharmaceutically effective amount of antibody substance immunologically reactive with the common .beta. chain (CD18) of human leukocyte integrins and/or competes with mAb 60.3 for binding to human LFA-1.
公开/授权文献
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