发明授权
US5855917A Method for controlling body fat and/or body weight in animals and
pharmaceutical compositions for use therein comprising 20-carbon
conjugated unsaturated fatty acids
失效
用于控制动物体内脂肪和/或体重的方法和用于其中的药物组合物，其包含20-碳共轭不饱和脂肪酸
- 专利标题： Method for controlling body fat and/or body weight in animals and pharmaceutical compositions for use therein comprising 20-carbon conjugated unsaturated fatty acids
- 专利标题（中）： 用于控制动物体内脂肪和/或体重的方法和用于其中的药物组合物，其包含20-碳共轭不饱和脂肪酸
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申请号： US759496申请日： 1996-12-04
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公开(公告)号： US5855917A公开(公告)日： 1999-01-05
- 发明人: Mark E. Cook , Yeonhwa Park , Michael W. Pariza
- 申请人： Mark E. Cook , Yeonhwa Park , Michael W. Pariza
- 申请人地址： WI Madison
- 专利权人： Wisconsin Alumni Research Foundation
- 当前专利权人： Wisconsin Alumni Research Foundation
- 当前专利权人地址： WI Madison
- 主分类号： C12P7/64
- IPC分类号： C12P7/64 ; A61K31/201 ; A61K31/202 ; A61P3/04 ; A61P3/06 ; C07C51/353 ; C07C57/02 ; C07C57/03 ; A61K9/50 ; C07C5/22 ; C07C5/23 ; C07C5/25
摘要：
Methods of inhibiting lipoprotein lipase and controlling the body fat and the body weight of an animal employ an effective amount of at least one 20 carbon, conjugated, unsaturated, fatty acid. Pharmaceutical compositions for use in the method are also disclosed. The 20-carbon conjugated fatty acids are selected from an eicosadienoic acid, an eicosatrienoic acid, and an eicosatetraenoic acid. Preferably, the fatty acids are 11,13-eicosadienoic acid; 12,14-eicosadienoic acid; 8,11,13-eicosatrienoic acid; 5,8,11,13-eicosatetraenoic acid; 5,8,12,14-eicosatetraenoic acid, or an ester, salt, or mixture thereof.
公开/授权文献
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