发明授权
- 专利标题: Optically active compound
- 专利标题(中): 光学活性化合物
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申请号: US817872申请日: 1997-05-01
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公开(公告)号: US5856480A公开(公告)日: 1999-01-05
- 发明人: Nobuo Mochizuki , Nobuhiro Umeda , Seiichi Uchida
- 申请人: Nobuo Mochizuki , Nobuhiro Umeda , Seiichi Uchida
- 申请人地址: JPX Tokyo
- 专利权人: Nippon Soda Co., Ltd.
- 当前专利权人: Nippon Soda Co., Ltd.
- 当前专利权人地址: JPX Tokyo
- 优先权: JPX6-301674 19941111
- 主分类号: C07D237/04
- IPC分类号: C07D237/04 ; A61K31/50
摘要:
The present invention is directed to (R)-(-)-4,5-dihydro-5-methyl-6-�4-�(2-propyl-3-oxo-1-cyclohexenyl)amino!phenyl!-3(2H)-pyridazinone, the crystalline form thereof and a method for manufacturing the said compound and the said crystalline form.The compound of the present invention has excellent inhibitory effect on platelet aggregation while giving less side effect, and therefore, it is useful to utilize the compound as an antithrombotic drug. In addition, the compound of the present invention has bronchodialatic effect as well, and it is therefore useful to utilize the compound for chemotherapy of chronic obstructive lung disease, such as asthma and bronchitis.Moreover, the compound of the present invention is useful for chemotherapy of the diseases relating to the concentration of cAMP in cells, such as hypertension, ulcer, diabetes mellitus and cancer.Again, crystalline form of the said compound is the most suitable form in order to supply stable and homogeneous bulk thereof.
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