发明授权
US5856567A Continuous hydrolysis process for preparing
2-hydroxy-4-methylthiobutanioc acid or salts thereof
失效
用于制备2-羟基-4-甲硫基丁酸或其盐的连续水解方法
- 专利标题: Continuous hydrolysis process for preparing 2-hydroxy-4-methylthiobutanioc acid or salts thereof
- 专利标题(中): 用于制备2-羟基-4-甲硫基丁酸或其盐的连续水解方法
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申请号: US647161申请日: 1996-05-21
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公开(公告)号: US5856567A公开(公告)日: 1999-01-05
- 发明人: Yung C. Hsu , Thomas F. Blackburn , Paul F. Pellegrin , Allen H. Kranz , James M. Willock
- 申请人: Yung C. Hsu , Thomas F. Blackburn , Paul F. Pellegrin , Allen H. Kranz , James M. Willock
- 申请人地址: MO St. Louis
- 专利权人: Novus International, Inc.
- 当前专利权人: Novus International, Inc.
- 当前专利权人地址: MO St. Louis
- 主分类号: A23K1/16
- IPC分类号: A23K1/16 ; B01J14/00 ; B01J19/18 ; B01J19/24 ; C07C319/18 ; C07C319/20 ; C07C323/52 ; C07C323/60 ; C07C381/00 ; C07C51/42
摘要:
A continuous process for the preparation of 2-hydroxy-4-methylthiobutanoic acid or a salt thereof which includes introducing an aqueous mineral acid into a nitrile hydrolysis reactor including a continuous stirred tank reactor and introducing 2-hydroxy-4-methylthiobutanenitrile into the nitrile hydrolysis reactor. 2-hydroxy-4-methylthiobutanenitrile is continually hydrolyzed within the nitrile hydrolysis reactor to produce a nitrile hydrolysis reactor product stream containing 2-hydroxy-4-methylthiobutanamide. The nitrile hydrolysis reactor product stream is continuously introduced into an amide hydrolysis flow reactor. 2-hydroxy-4-methylthiobutanamide is continually hydrolyzed within the amide hydrolysis flow reactor to produce an aqueous hydrolyzate product containing 2-hydroxy-4-methylthiobutanoic acid. 2-hydroxy-4-methylthiobutanoic acid is recovered from the aqueous hydrolyzate product.
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