发明授权
US5858705A Polynucleotides encoding human DNA ligase III and methods of using these
polynucleotides
失效
编码人DNA连接酶III的多核苷酸和使用这些多核苷酸的方法
- 专利标题： Polynucleotides encoding human DNA ligase III and methods of using these polynucleotides
- 专利标题（中）： 编码人DNA连接酶III的多核苷酸和使用这些多核苷酸的方法
-
申请号： US464402申请日： 1995-06-05
-
公开(公告)号： US5858705A公开(公告)日： 1999-01-12
- 发明人: Ying-Fei Wei , Guo-Liang Yu , William A. Haseltine
- 申请人： Ying-Fei Wei , Guo-Liang Yu , William A. Haseltine
- 申请人地址： MD Rockville
- 专利权人： Human Genome Sciences, Inc.
- 当前专利权人： Human Genome Sciences, Inc.
- 当前专利权人地址： MD Rockville
- 主分类号： A61K48/00
- IPC分类号： A61K48/00 ; C12N9/00 ; C12N15/52 ; C12N15/63
摘要：
A human DNA Ligase III polypeptide and DNA (RNA) encoding such polypeptide and a procedure for producing such polypeptide by recombinant techniques are disclosed. Also disclosed are methods for utilizing such polypeptide via gene therapy for the treatment of disorders associated with a defect in DNA Ligase III. Antagonists against such polypeptides and their use as a therapeutic to destroy unwanted cells are also disclosed. Diagnostic assays to detect mutant DNA Ligase III genes are also disclosed.
公开/授权文献
- US4522026A Power/torque limiter unit for free turbine type engines 公开/授权日：1985-06-11
信息查询
