发明授权
- 专利标题: Dihydropyridine derivatives as bradykinin antagonist
- 专利标题(中): 二氢吡啶衍生物作为缓激肽拮抗剂
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申请号: US793561申请日: 1997-07-01
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公开(公告)号: US5859011A公开(公告)日: 1999-01-12
- 发明人: Fumitaka Ito , Hiroshi Kondo , David L. Hageman , John A. Lowe, III , Susumu Nakanishi , Fredric J. Vinick
- 申请人: Fumitaka Ito , Hiroshi Kondo , David L. Hageman , John A. Lowe, III , Susumu Nakanishi , Fredric J. Vinick
- 申请人地址: NY New York
- 专利权人: Pfizer Inc.
- 当前专利权人: Pfizer Inc.
- 当前专利权人地址: NY New York
- 优先权: WOXPCT/JP94/01398 19940824
- 主分类号: C07D487/08
- IPC分类号: C07D487/08 ; A61K31/4427 ; A61K31/4433 ; A61K31/445 ; A61K31/451 ; A61K31/495 ; A61K31/505 ; A61P9/00 ; A61P11/00 ; A61P17/00 ; A61P25/04 ; A61P29/00 ; A61P31/12 ; A61P37/08 ; A61P43/00 ; C07D211/90 ; C07D401/06 ; C07D401/12 ; C07D405/06 ; C07D409/06 ; C07D451/04 ; C07D453/02 ; C07D471/08 ; A61K31/50
摘要:
Compound of formula (1) and their pharmaceutically acceptable salts wherein A1,A2,R1, R2,R3,R4,X are as defined in the specification have excellent bradykinin antagonistic activity. ##STR1##