发明授权
- 专利标题： Human zinc binding proteins
- 专利标题（中）： 人锌结合蛋白
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申请号： US786606申请日： 1997-01-21
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公开(公告)号： US5861495A公开(公告)日： 1999-01-19
- 发明人: Jennifer L. Hillman , Janice Au-Young , Roger Coleman , Surya K. Goli
- 申请人： Jennifer L. Hillman , Janice Au-Young , Roger Coleman , Surya K. Goli
- 申请人地址： CA Palo Alto
- 专利权人： Incyte Pharmaceuticals, Inc.
- 当前专利权人： Incyte Pharmaceuticals, Inc.
- 当前专利权人地址： CA Palo Alto
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; C07K14/47 ; C12N15/12 ; C07H21/02 ; C07H21/04
摘要：
The present invention provides three zinc binding proteins (designated individually as ZB-1, ZB-2, and ZB-3, and collectively as ZB) and polynucleotides which identify and encode ZB. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding ZB and a method for producing ZB. The invention also provides for use of ZB and agonists, antibodies, or antagonists specifically binding ZB, in the prevention and treatment of diseases associated with expression of ZB. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding ZB for the treatment of diseases associated with the expression of ZB. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding ZB.
公开/授权文献
- US4079642A Strap wrench 公开/授权日：1978-03-21
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