发明授权
- 专利标题: Reduction of skin irritation during electrotransport delivery
- 专利标题(中): 电运输期间减少皮肤刺激
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申请号: US895096申请日: 1997-07-16
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公开(公告)号: US5865792A公开(公告)日: 1999-02-02
- 发明人: Philip W. Ledger , Michel J.N. Cormier , Patricia S. Campbell
- 申请人: Philip W. Ledger , Michel J.N. Cormier , Patricia S. Campbell
- 申请人地址: CA Palo Alto
- 专利权人: ALZA Corporation
- 当前专利权人: ALZA Corporation
- 当前专利权人地址: CA Palo Alto
- 主分类号: A61N1/30
- IPC分类号: A61N1/30 ; A61N1/32
摘要:
The invention is directed to a composition and product for use in an electrotransport device. The composition includes an ionized drug, an anti-inflammatory agent and a solvent. Preferably, the anti-inflammatory agent is hydrocortisone or esters thereof, and the solvent is an alcohol, a glycol, a glycerol, a cyclodextrin, a nonionic surfactant or mixtures thereof. The composition preferably further includes a gel matrix that is a swellable, hydrophilic polymer, a water soluble hydrophilic polymer or a solid polymer. A hydrophobic polymer and/or additives may also be included.
公开/授权文献
- US5312257A Color-coded training method 公开/授权日:1994-05-17
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