发明授权
US5869651A Hydrazide derivatives of polyamides and their medical use as chelating
agents
失效
聚酰胺的酰肼衍生物及其作为螯合剂的医疗用途
- 专利标题: Hydrazide derivatives of polyamides and their medical use as chelating agents
- 专利标题(中): 聚酰胺的酰肼衍生物及其作为螯合剂的医疗用途
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申请号: US190143申请日: 1994-08-08
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公开(公告)号: US5869651A公开(公告)日: 1999-02-09
- 发明人: Richard J. Himmelsbach , P.ang.l Rongved , Jo Klaveness , Per Strande , Harald Dugstad
- 申请人: Richard J. Himmelsbach , P.ang.l Rongved , Jo Klaveness , Per Strande , Harald Dugstad
- 申请人地址: CA Sunnyvale
- 专利权人: Nycomed Salutar
- 当前专利权人: Nycomed Salutar
- 当前专利权人地址: CA Sunnyvale
- 优先权: GBX9115375 19910717
- 主分类号: A61K51/00
- IPC分类号: A61K51/00 ; C07C243/34 ; C07C259/06 ; C07C311/31 ; C07C317/28 ; C07D257/02 ; C07D259/00 ; C07F5/00 ; C07F9/24 ; C07F9/6524 ; C09K3/00 ; C07D498/08 ; C07F15/02
摘要:
The invention relates to certain substituted derivatives of aminopolycarboxylic acids and metal chelates thereof. The compounds are particularly suitable for use as diagnostic agent. For example, the compounds can be used as radiodiagnostic agents, detoxification agents and contrast agents for diagnostic imaging processes. In particular, the high relaxivity paramagnetic metal chelates of substituted aminopolycarboxylic acids are especially suited for use as magnetic resonance imaging contrast agents.
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