发明授权
- 专利标题: Vector vaccines of bovine herpesvirus I
- 专利标题(中): 牛疱疹病毒I的载体疫苗
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申请号: US344833申请日: 1994-11-23
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公开(公告)号: US5874280A公开(公告)日: 1999-02-23
- 发明人: Gunther Keil
- 申请人: Gunther Keil
- 申请人地址: NLX Arnhem
- 专利权人: Akzo Nobel N.V.
- 当前专利权人: Akzo Nobel N.V.
- 当前专利权人地址: NLX Arnhem
- 优先权: EPX93203274 19931123
- 主分类号: C07K14/06
- IPC分类号: C07K14/06 ; C12N7/00 ; C12N7/01 ; C12N15/869 ; A61K39/245 ; C07H21/04
摘要:
The present invention is concerned with a Bovine Herpesvirus I (BHV-I) mutant comprising a heterologous gene introduced into a section of the BHV-I genome. The invention also relates to a vector vaccine comprising such a BHV-I mutant which expresses a heterologous polypeptide derived from a bovine pathogen and induces an adequate immune response in an inoculated host against both FHV an the bovine pathogen. Furthermore, the invention relates to a method for obtaining a BHV-I mutant by self-selection.
公开/授权文献
- US4456414A Quick coupling apparatus for interchangeable truck bodies 公开/授权日:1984-06-26
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