发明授权
US5874404A Immunoglobulin E receptor .alpha.-chain inhibits IgE production and
secondary allergic responses
失效
免疫球蛋白E受体α链可抑制IgE产生和继发性过敏反应
- 专利标题： Immunoglobulin E receptor .alpha.-chain inhibits IgE production and secondary allergic responses
- 专利标题（中）： 免疫球蛋白E受体α链可抑制IgE产生和继发性过敏反应
-
申请号： US238027申请日： 1994-05-03
-
公开(公告)号： US5874404A公开(公告)日： 1999-02-23
- 发明人: Chisei Ra , Koji Naito , Minoru Hirama , Ko Okumura , Yukiyoshi Yanagihara
- 申请人： Chisei Ra , Koji Naito , Minoru Hirama , Ko Okumura , Yukiyoshi Yanagihara
- 申请人地址： JPX Chiba JPX Osaka
- 专利权人： Ra; Chisei,The Green Cross Corporation
- 当前专利权人： Ra; Chisei,The Green Cross Corporation
- 当前专利权人地址： JPX Chiba JPX Osaka
- 优先权： JPX4-229227 19920804; JPX4-213002 19920810; JPX4-270513 19921008; JPX4-270514 19921008; JPX4-270515 19921008; JPX5-208217 19930729; JPX5-197341 19930809; JPX5-251605 19931007; JPX5-251606 19931007; JPX5-251608 19931007; JPX5-261355 19931019; JPX5-264802 19931022
- 主分类号： A01K67/027
- IPC分类号： A01K67/027 ; A61K38/00 ; A61K38/11 ; C12N15/85
摘要：
Disclosed is an antiallergic composition comprising, as an active ingredient, a peptide which is capable of binding to human IgE, more specifically the high-affinity immunoglobulin E receptor .alpha.-chain or a soluble fragment, which is capable of binding to human IgE, or the high-affinity immunoglobulin E receptor .alpha.-chain. The composition is clinically useful for blocking allergic responses. An animal model for use in the screening of prophylactic and therapeutic compositions for IgE-related diseases is also disclosed.
公开/授权文献
信息查询
