发明授权
- 专利标题: Enhancer sequence for modulating expression in epithelial cells
- 专利标题(中): 用于调节上皮细胞表达的增强子序列
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申请号: US465981申请日: 1995-06-06
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公开(公告)号: US5874415A公开(公告)日: 1999-02-23
- 发明人: Donald Kufe , Miyako Abe
- 申请人: Donald Kufe , Miyako Abe
- 申请人地址: MA Boston
- 专利权人: Dana-Farber Cancer Institute, Inc.
- 当前专利权人: Dana-Farber Cancer Institute, Inc.
- 当前专利权人地址: MA Boston
- 主分类号: A61K48/00
- IPC分类号: A61K48/00 ; C12N15/85 ; A01N43/04 ; A61K38/16 ; C07H21/04
摘要:
Isolated DNA encompassing the DF3 enhancer as well as a sequence encoding a heterologous polypeptide provides epithelial tissue-selective gene expression of the heterologous polypeptide, useful in methods of therapy.
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